Molly didn't have to be an empath to get the sudden change in emotion in Liz. Nor did she have to be a genius to figure out that she connected Harry's circumstance with Peter.

"Shit. Sorry. I didn't mean to bring the conversation down. Just grab whatever happiness you can, when you can. Life is too short. If this is all you get, then grab hold with two hands and experience the shit out of life. If you get more, then that's bonus. Just don't plan, wish and hope for it to change. It will only piss you off when it doesn't happen."

She had no illusions that whatever this held for her with Sam and potentially Bo, was only going to happen here. They were not from her world. No amount of wishing would change that.